The sealing property of medicine bags and the preservation of medicines

The sealing of medicine bags plays a vital role in the preservation of medicines. The following is a detailed analysis of the relationship between the sealing of medicine bags and the preservation of medicines:

Ⅰ. The importance of the sealing of medicine bags

1. Prevent medicines from getting damp: A humid environment can easily cause medicines to deteriorate, mold or lose their activity. Medicine bags with good sealing properties can effectively isolate external moisture, keep medicines dry, and thus extend their shelf life.

2. Isolate microbial contamination: Microorganisms in the air, such as bacteria and mold, may contaminate drugs and affect their quality and safety. A well-sealed medicine bag can form an effective barrier to prevent the invasion of microorganisms and protect drugs from contamination.

3. Maintain drug quality: Good sealing can maintain the original state of drugs and reduce the loss of drugs during storage, such as volatilization and oxidation, thereby ensuring the effectiveness and safety of drugs.

Ⅱ. Requirements for drug storage

1. Dryness: Drugs should be stored in a dry environment to avoid moisture. A humid environment will accelerate the deterioration of drugs, so it is crucial to keep the sealing of the medicine bag.

2. Coolness: High temperature will accelerate the deterioration of drugs, so drugs should be stored in a cool place. Generally, the most suitable storage temperature for drugs is between 15 and 25 degrees Celsius.

3. Avoid light: Some drugs are sensitive to light and should be stored in a dark place. Long-term light exposure may cause drug deterioration or increased toxicity.

Ⅲ. Testing methods for drug bag sealing

In order to ensure the sealing of drug bags, appropriate testing methods need to be used for verification. Common drug packaging sealing integrity testing methods include physical integrity testing methods (such as pressure/vacuum decay, etc.) and microbial challenge methods. These methods can directly or indirectly prove the integrity of packaging sealing, thereby ensuring the safety and effectiveness of drugs during production, storage and transportation.